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mmp3 polyclonal antibody  (Proteintech)


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    Proteintech mmp3 polyclonal antibody
    Ddrgk1 cKO mice showed diminished SOX9 and Aggrecan expression and increased <t>MMP3</t> expression in intervertebral discs. (A and D) (A) SOX9 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (D) Statistical analyses of SOX9 + cells rate in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (B and E) (B) MMP3 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (E) Quantitative analyses of MMP3 expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (C and F) (C) Aggrecan IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (F) Quantitative analyses of Aggrecan expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. Scale bar: 50 μm. Data are represented as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, ns represents no statistical difference between data
    Mmp3 Polyclonal Antibody, supplied by Proteintech, used in various techniques. Bioz Stars score: 96/100, based on 332 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mmp3 polyclonal antibody/product/Proteintech
    Average 96 stars, based on 332 article reviews
    mmp3 polyclonal antibody - by Bioz Stars, 2026-02
    96/100 stars

    Images

    1) Product Images from "DDRGK1 preserves intervertebral disc development through ufmylation"

    Article Title: DDRGK1 preserves intervertebral disc development through ufmylation

    Journal: Cellular and Molecular Life Sciences: CMLS

    doi: 10.1007/s00018-025-06034-8

    Ddrgk1 cKO mice showed diminished SOX9 and Aggrecan expression and increased MMP3 expression in intervertebral discs. (A and D) (A) SOX9 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (D) Statistical analyses of SOX9 + cells rate in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (B and E) (B) MMP3 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (E) Quantitative analyses of MMP3 expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (C and F) (C) Aggrecan IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (F) Quantitative analyses of Aggrecan expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. Scale bar: 50 μm. Data are represented as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, ns represents no statistical difference between data
    Figure Legend Snippet: Ddrgk1 cKO mice showed diminished SOX9 and Aggrecan expression and increased MMP3 expression in intervertebral discs. (A and D) (A) SOX9 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (D) Statistical analyses of SOX9 + cells rate in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (B and E) (B) MMP3 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (E) Quantitative analyses of MMP3 expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (C and F) (C) Aggrecan IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (F) Quantitative analyses of Aggrecan expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. Scale bar: 50 μm. Data are represented as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, ns represents no statistical difference between data

    Techniques Used: Expressing, Immunohistochemistry



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    Ddrgk1 cKO mice showed diminished SOX9 and Aggrecan expression and increased <t>MMP3</t> expression in intervertebral discs. (A and D) (A) SOX9 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (D) Statistical analyses of SOX9 + cells rate in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (B and E) (B) MMP3 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (E) Quantitative analyses of MMP3 expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (C and F) (C) Aggrecan IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (F) Quantitative analyses of Aggrecan expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. Scale bar: 50 μm. Data are represented as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, ns represents no statistical difference between data
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    Image Search Results


    Validation of the TIMP1 gene silencing OA rat model. (A) Body weight changes in four groups during model construction. (B,C) Serum levels of TNF-α and IL-1β detected by ELISA. (D) Toluidine blue staining of cartilage tissue sections with semiquantitative analysis. (E) HE staining showing histological changes in cartilage tissue. (F) IHC staining and expression analysis of Collagen II, MMP3, MMP13, and TIMP1 in femoral cartilage tissues.

    Journal: Frontiers in Pharmacology

    Article Title: Combined multi-omics approach to identify the key metabolites, key microorganisms and biomarkers correlated with the neutrophil extracellular traps-associated gene TIMP1 in osteoarthritis

    doi: 10.3389/fphar.2025.1665228

    Figure Lengend Snippet: Validation of the TIMP1 gene silencing OA rat model. (A) Body weight changes in four groups during model construction. (B,C) Serum levels of TNF-α and IL-1β detected by ELISA. (D) Toluidine blue staining of cartilage tissue sections with semiquantitative analysis. (E) HE staining showing histological changes in cartilage tissue. (F) IHC staining and expression analysis of Collagen II, MMP3, MMP13, and TIMP1 in femoral cartilage tissues.

    Article Snippet: For immunohistochemical analysis, 3 μm paraffin sections were incubated with primary antibodies against Collagen II (Huabio, ER1906-48, Hangzhou, China; 1:100), MMP3 (Affinity, AF0217, Liyang, China; 1:50), MMP13 (Bioss, bs-10581R, Beijing, China; 1:100), and TIMP-1 (Bioss, bs-4600R, Beijing, China; 1:100), all diluted in 2% BSA.

    Techniques: Biomarker Discovery, Enzyme-linked Immunosorbent Assay, Staining, Immunohistochemistry, Expressing

    Ddrgk1 cKO mice showed diminished SOX9 and Aggrecan expression and increased MMP3 expression in intervertebral discs. (A and D) (A) SOX9 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (D) Statistical analyses of SOX9 + cells rate in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (B and E) (B) MMP3 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (E) Quantitative analyses of MMP3 expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (C and F) (C) Aggrecan IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (F) Quantitative analyses of Aggrecan expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. Scale bar: 50 μm. Data are represented as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, ns represents no statistical difference between data

    Journal: Cellular and Molecular Life Sciences: CMLS

    Article Title: DDRGK1 preserves intervertebral disc development through ufmylation

    doi: 10.1007/s00018-025-06034-8

    Figure Lengend Snippet: Ddrgk1 cKO mice showed diminished SOX9 and Aggrecan expression and increased MMP3 expression in intervertebral discs. (A and D) (A) SOX9 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (D) Statistical analyses of SOX9 + cells rate in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (B and E) (B) MMP3 IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (E) Quantitative analyses of MMP3 expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. (C and F) (C) Aggrecan IHC staining images in the central region of nucleus pulposus and superior cartilage endplate of WT and Ddrgk1 cKO mice at 12 d, 22 d, 30 d, 6 m, and after LSI surgery. (F) Quantitative analyses of Aggrecan expression in the nucleus pulposus and cartilage endplate regions between WT and Ddrgk1 cKO mice at the corresponding time points above. n = 6. Scale bar: 50 μm. Data are represented as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, ns represents no statistical difference between data

    Article Snippet: MMP3 Polyclonal antibody , Proteintech , Wuhan, Hubei, China , Cat# 17873-1-AP.

    Techniques: Expressing, Immunohistochemistry